Nanovesicles From Red Blood Cells: A Potential Dual-Mode (Chemo Photothermal/Photodynamic) Therapeutic Approach

Rishi Kumar Mishra, Dr. Riyazul Hasan Khan

Volume 6, Issue 1 2022

Page: 23-30

Abstract

Micelles, polymeric nanoparticles, and liposomes are all examples of nanoparticles with cancer treatment approval. The main aim of the study is Nanovesicles from red blood cells: a potential dual-mode (chemophotothermal/photodynamic) therapeutic approach. All of the cell culture reagents, including foetal bovine serum (FBS), trypsin, MTT (3-(4,5-dimethylthiazol-2-yl)-2,5- diphenyltetrazolium bromide), and dichlorofluorescein diacetate (H2DCFDA), were purchased from Invitrogen. Both the hydrophobic drug CPT and the amphiphilic photosensitizer ICG have been integrated into the bilayer membranes of the target cells, RBCs are able to re-assemble into stable nanovesicles.

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